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1

Nuclear localization of Klotho in brain: an anti-aging protein

Dwight C. German, Ida Khobahy, Johanne Pastor, Makoto Kuro-o, Xinran Liu

Journal:

Neurobiology of Aging

Year:

2012

Language:

english

File:

PDF, 2.21 MB

english, 2012

2

Vitamin D receptor agonists increase klotho and osteopontin while decreasing aortic calcification in mice with chronic kidney disease fed a high phosphate diet

Lau, Wei Ling, Leaf, Elizabeth M, Hu, Ming Chang, Takeno, Marc M, Kuro-o, Makoto, Moe, Orson W, Giachelli, Cecilia M

Journal:

Kidney International

Year:

2012

Language:

english

File:

PDF, 1.00 MB

english, 2012

3

Urinary phosphate-containing nanoparticle contributes to inflammation and kidney injury in a salt-sensitive hypertension rat model

Wang, Qin, Ishizawa, Kenichi, Li, Jinping, Fujii, Wataru, Nemoto, Yoshikazu, Yamazaki, Osamu, Tamura, Yoshifuru, Miura, Yutaka, Nie, Xuedan, Abe, Ryo, Segawa, Hiroko, Kuro-O, Makoto, Shibata, Shigeru

Journal:

Communications Biology

Year:

2020

File:

PDF, 3.13 MB

2020

4

Overview of the FGF23-Klotho axis

Journal:

Pediatric Nephrology

Year:

2010

Language:

english

File:

PDF, 197 KB

english, 2010

5

Molecular Regulation of Phosphate Metabolism by Fibroblast Growth Factor-23–Klotho System

Cheng, Chung-Yi, Kuro-o, Makoto, Razzaque, Mohammed S.

Journal:

Advances in Chronic Kidney Disease

Year:

2011

Language:

english

File:

PDF, 232 KB

english, 2011

6

PTH, vitamin D, and the FGF-23-klotho axis and heart: going beyond the confines of nephrology

Navarro-García, José Alberto, Fernández-Velasco, María, Delgado, Carmen, Delgado, Juan F., Kuro-o, Makoto, Ruilope, Luis Miguel, Ruiz-Hurtado, Gema

Journal:

European Journal of Clinical Investigation

Year:

2018

Language:

english

File:

PDF, 257 KB

english, 2018

7

Improvement of multiple pathophysiological phenotypes of klotho (kl/kl) mice by adenovirus-mediated expression of the klotho gene

Takako Shiraki-Iida, Akihiro Iida, Yoko Nabeshima, Hideharu Anazawa, Satoshi Nishikawa, Masaki Noda, Makoto Kuro-o, Yo-ichi Nabeshima

Journal:

The Journal of Gene Medicine

Year:

2000

Language:

english

File:

PDF, 604 KB

english, 2000

8

Role of Klotho in Aging, Phosphate Metabolism, and CKD

George B. John, Chung-Yi Cheng, Makoto Kuro-o

Journal:

American Journal of Kidney Diseases

Year:

2011

Language:

english

File:

PDF, 697 KB

english, 2011

9

The FGF23 and Klotho system beyond mineral metabolism

Journal:

Clinical and Experimental Nephrology

Year:

2017

Language:

english

File:

PDF, 397 KB

english, 2017

10

Expression of myosin isozymes during the developmental stage and their redistribution induced by pressure overload.

TSUCHIMOCHI, Hidetsugu, KURO-O, Makoto, TAKAKU, Fumimaro, YOSHIDA, Kohsuke, KAWANA, Masatoshi, KIMATA, Shin-ichi, YAZAKI, Yoshio

Journal:

Japanese Circulation Journal

Year:

1986

File:

PDF, 1.22 MB

1986

11

Production of Nitric Oxide, but Not Prostacyclin, Is Reduced in Klotho Mice

Nakamura, Tetsuya, Saito, Yuichiro, Ohyama, Yoshio, Masuda, Hiroaki, Sumino, Hiroyuki, Kuro-o, Makoto, Nabeshima, Youichi, Nagai, Ryozo, Kurabayashi, Masahiko

Journal:

The Japanese Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 416 KB

english, 2002

12

High Salt Diet Impacts the Risk of Sarcopenia Associated with Reduction of Skeletal Muscle Performance in the Japanese Population

Yoshida, Yasuko, Kosaki, Keisei, Sugasawa, Takehito, Matsui, Masahiro, Yoshioka, Masaki, Aoki, Kai, Kuji, Tomoaki, Mizuno, Risuke, Kuro-o, Makoto, Yamagata, Kunihiro, Maeda, Seiji, Takekoshi, Kazuhiro

Journal:

Year:

2020

File:

PDF, 1.96 MB

2020

13

12 Loss of Gastric Interstitial Cells of Cajal and Impaired Electrical Pacemaking in Klotho Mice, an Animal Model of Aging

Ferenc Izbeki, Andrea Lorincz, David T. Asuzu, Laura Popko, David L. Young, Michael R. Bardsley, Yujiro Hayashi, Makoto Kuro-o, Gianrico Farrugia, Tamas Ordog

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 74 KB

english, 2010

14

The parathyroid is a target organ for FGF23 in rats

Ben-Dov, Iddo Z., Galitzer, Hillel, Lavi-Moshayoff, Vardit, Goetz, Regina, Kuro-o, Makoto, Mohammadi, Moosa, Sirkis, Roy, Naveh-Many, Tally, Silver, Justin

Journal:

Journal of Clinical Investigation

Year:

2007

Language:

english

File:

PDF, 673 KB

english, 2007

15

Roles of Vascular Smooth Muscles in Atherosclerosis.

NAGAI, Ryozo, AIKAWA, Nasanori, KURO-O, Makoto, YAZAKI, Yoshio

Journal:

Internal Medicine

Year:

1995

Language:

english

File:

PDF, 1.77 MB

english, 1995

16

Identification of the HumanKlothoGene and Its Two Transcripts Encoding Membrane and SecretedKlothoProtein

Yutaka Matsumura, Hiroki Aizawa, Takako Shiraki-Iida, Ryozo Nagai, Makoto Kuro-o, Yo-ichi Nabeshima

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 1.19 MB

english, 1998

17

Myocardial damage and coronary artery lesion due to Kawasaki disease: Evaluation with ultrafast CT

Kuroe, Kenji, Kohata, Tohru, Kamiya, Tetsuro, Suzuki, Atsuko, Ono, Yasuo, Echigo, Shigeyuki, Naito, Hiroaki, Takamiya, Makoto

Journal:

Progress in Pediatric Cardiology

Year:

1992

Language:

english

File:

PDF, 102 KB

english, 1992

18

The Klotho gene family and the endocrine fibroblast growth factors

Kurosu, Hiroshi, Kuro-o, Makoto

Journal:

Current Opinion in Nephrology & Hypertension

Year:

2008

Language:

english

File:

PDF, 106 KB

english, 2008

19

Klothoinsufficiency causes decrease of ribosomal RNA gene transcription activity, cytoplasmic RNA and rough ER in the spinal anterior horn cells

Yorito Anamizu, Hiroshi Kawaguchi, Atsushi Seichi, Shinji Yamaguchi, Emiko Kawakami, Naotoshi Kanda, Shiro Matsubara, Makoto Kuro-o, Yoichi Nabeshima, Kozo Nakamura, Kiyomitsu Oyanagi

Journal:

Acta Neuropathologica

Year:

2005

Language:

english

File:

PDF, 664 KB

english, 2005

20

Klotho gene delivery suppresses Nox2 expression and attenuates oxidative stress in rat aortic smooth muscle cells via the cAMP-PKA pathway

Yuhong Wang, Makoto Kuro-o, Zhongjie Sun

Journal:

Year:

2012

Language:

english

File:

PDF, 515 KB

english, 2012

21

Na+/Ca2+ exchanger-deficient mice have disorganized myofibrils and swollen mitochondria in cardiomyocytes

Koji Wakimoto, Hisako Fujimura, Takahiro Iwamoto, Toru Oka, Kinji Kobayashi, Satomi Kita, Sumiyo Kudoh, Makoto Kuro-o, Yo-ichi Nabeshima, Munekazu Shigekawa, Yuji Imai, Issei Komuro

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

2003

Language:

english

File:

PDF, 1.45 MB

english, 2003

22

Disease model: human aging

Journal:

Trends in Molecular Medicine

Year:

2001

Language:

english

File:

PDF, 221 KB

english, 2001

23

[AIP RENAL STONE DISEASE: 1st Annual International Urolithiasis Research Symposium - Indianapolis, Indiana (USA) (2-3 November 2006)] AIP Conference Proceedings - Aromatase Deficient Female Mice Demonstrate Altered Expression of Molecules Critical for Renal Calcium Reabsorption

Öz, Orhan K., Hajibeigi, Asghar, Cummins, Carolyn, van Abel, Monique, Bindels, René J., Kuro-o, Makoto, Pak, Charles Y. C., Zerwekh, Joseph E.

Year:

2007

File:

PDF, 928 KB

2007

24

Modulation of Klotho expression in injured muscle perturbs Wnt signaling and influences the rate of muscle growth

Welc, Steven S., Wehling‐Henricks, Michelle, Kuro‐o, Makoto, Thomas, Kyle A., Tidball, James G.

Journal:

Experimental Physiology

Year:

2019

File:

PDF, 2.11 MB

2019

25

Mud in the blood the role of protein-mineral complexes and extracellular vesicles in biomineralisation and calcification

Jahnen-Dechent, Willi, BÃ¼scher, Andrea, KÃ¶ppert, Sina, Heiss, Alexander, Kuro-o, Makoto, Smith, Edward R.

Journal:

Journal of Structural Biology

Year:

2020

File:

PDF, 2.00 MB

2020

26

Regulation of the Na+/K+ ATPase by Klotho

Mentor Sopjani, Ioana Alesutan, Miribane Dërmaku-Sopjani, Shuchen Gu, Christine Zelenak, Carlos Munoz, Ana Velic, Michael Föller, Kevin P. Rosenblatt, Makoto Kuro-o, Florian Lang

Journal:

Year:

2011

Language:

english

File:

PDF, 737 KB

english, 2011

27

Examination of smooth muscle cell lineage in arterial remodeling with smooth muscle specific marker: Smooth muscle myosin heavy chain

Hiroshi Iwata, Masataka Sata, Ichiro Manabe, Katsuhito Fujiu, Makoto Kuro-o, Ryozo Nagai

Journal:

Vascular Pharmacology

Year:

2006

Language:

english

File:

PDF, 85 KB

english, 2006

28

Molecular Cloning of RatklothocDNA: Markedly Decreased Expression ofklothoby Acute Inflammatory Stress

Yoshio Ohyama, Masahiko Kurabayashi, Hiroaki Masuda, Tetsuya Nakamura, Yasushi Aihara, Tadashi Kaname, Tatsuo Suga, Masashi Arai, Hiroki Aizawa, Yutaka Matsumura, Makoto Kuro-o, Yo-ichi Nabeshima, Ryo

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 1.35 MB

english, 1998

29

Amadori products promote cellular senescence activating insulin-like growth factor-1 receptor and down-regulating the antioxidant enzyme catalase

del Nogal-Ávila, María, Troyano-Suárez, Nuria, Román-García, Pablo, Cannata-Andía, Jorge B., Rodriguez-Puyol, Manuel, Rodriguez-Puyol, Diego, Kuro-O, Makoto, Ruiz-Torres, María P.

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2013

Language:

english

File:

PDF, 2.37 MB

english, 2013

30

The secreted Klotho protein restores phosphate retention and suppresses accelerated aging in Klotho mutant mice

Chen, Tso-Hsiao, Kuro-o, Makoto, Chen, Cheng-Hsien, Sue, Yuh-Mou, Chen, Yen-Cheng, Wu, Ho-Han, Cheng, Chung-Yi

Journal:

European Journal of Pharmacology

Year:

2013

Language:

english

File:

PDF, 550 KB

english, 2013

31

Klotho in health and disease

Journal:

Current Opinion in Nephrology & Hypertension

Year:

2012

Language:

english

File:

PDF, 273 KB

english, 2012

32

Disruption of the klotho Gene Causes Pulmonary Emphysema in Mice

Suga, Tatsuo, Kurabayashi, Masahiko, Sando, Yoshichika, Ohyama, Yoshio, Maeno, Toshitaka, Maeno, Yuri, Aizawa, Hiroki, Matsumura, Yutaka, Kuwaki, Tomoyuki, Kuro-o, Makoto, Nabeshima, Yo-ichi, Nagai, R

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2000

Language:

english

File:

PDF, 1.01 MB

english, 2000

33

The impact of preserved Klotho gene expression on antioxidative stress activity in healthy kidney

Kimura, Takaaki, Shiizaki, Kazuhiro, Akimoto, Tetsu, Shinzato, Takahiro, Shimizu, Toshihiro, Kurosawa, Akira, Kubo, Taro, Nanmoku, Koji, Kuro-o, Makoto, Yagisawa, Takashi

Journal:

American journal of physiology. Renal physiology

Year:

2018

Language:

english

File:

PDF, 369 KB

english, 2018

34

Development of identification and the new treatment of the novel therapeutic target of arteriosclerosis

Journal:

Year:

2017

Language:

english

File:

PDF, 167 KB

english, 2017

35

Klotho, phosphate and FGF-23 in ageing and disturbed mineral metabolism

Journal:

Nature Reviews Nephrology (formerly Nature Clinical Practice Nephrology)

Year:

2013

Language:

english

File:

PDF, 1013 KB

english, 2013

36

[Advances in Experimental Medicine and Biology] Endocrine FGFs and Klothos Volume 728 ||

Year:

2012

Language:

english

File:

PDF, 3.82 MB

english, 2012

37

Novel treatment strategies for chronic kidney disease: insights from the animal kingdom

Stenvinkel, Peter, Painer, Johanna, Kuro-o, Makoto, Lanaspa, Miguel, Arnold, Walter, Ruf, Thomas, Shiels, Paul G., Johnson, Richard J.

Journal:

Nature Reviews Nephrology (formerly Nature Clinical Practice Nephrology)

Year:

2018

Language:

english

File:

PDF, 2.72 MB

english, 2018

38

Modulation of Klotho expression in injured muscle perturbs Wnt signaling and influences the rate of muscle growth

Welc, Steven S., Wehling‐Henricks, Michelle, Kuro‐o, Makoto, Thomas, Kyle A., Tidball, James G.

Journal:

Experimental Physiology

Year:

2019

Language:

english

File:

PDF, 2.11 MB

english, 2019

39

Klotho Protein Protects against Endothelial Dysfunction

Yuichiro Saito, Takahiro Yamagishi, Tetsuya Nakamura, Yoshio Ohyama, Hiroki Aizawa, Tatsuo Suga, Yutaka Matsumura, Hiroaki Masuda, Masahiko Kurabayashi, Makoto Kuro-o, Yo-ichi Nabeshima, Ryozo Nagai

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 122 KB

english, 1998

40

Heterogeneity in smooth muscle cell population accumulating in the neointimas and the media of poststenotic dilatation of the rabbit carotid artery

Ei-ichi Okamoto, Kohji Imataka, Jun Fujii, Makoto Kuro-o, Ken-ichi Nakahara, Hiroshi Nishimura, Yoshio Yazaki, Ryozo Nagai

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 1.92 MB

english, 1992

41

Cardioprotection by Klotho through downregulation of TRPC6 channels in the mouse heart

Xie, Jian, Cha, Seung-Kuy, An, Sung-Wan, Kuro-o, Makoto, Birnbaumer, Lutz, Huang, Chou-Long

Journal:

Nature Communications

Year:

2012

Language:

english

File:

PDF, 1.75 MB

english, 2012

42

Association between Serum Soluble Klotho Levels and Mortality in Chronic Hemodialysis Patients

Otani-Takei, Naoko, Masuda, Takahiro, Akimoto, Tetsu, Honma, Sumiko, Watanabe, Yuko, Shiizaki, Kazuhiro, Miki, Takuya, Kusano, Eiji, Asano, Yasushi, Kuro-o, Makoto, Nagata, Daisuke

Journal:

International Journal of Endocrinology

Year:

2015

Language:

english

File:

PDF, 1.64 MB

english, 2015

43

Association of calciprotein particles measured by a new method with coronary artery plaque in patients with coronary artery disease: A cross-sectional study

Nakazato, Jun, Hoshide, Satoshi, Wake, Minoru, Miura, Yutaka, Kuro-o, Makoto, Kario, Kazuomi

Journal:

Journal of Cardiology

Year:

2019

Language:

english

File:

PDF, 815 KB

english, 2019

44

Aromatase Deficiency Causes Altered Expression of Molecules Critical for Calcium Reabsorption in the Kidneys of Female Mice

Orhan K Öz, Asghar Hajibeigi, Kevin Howard, Carolyn L Cummins, Monique van Abel, Rene JM Bindels, R Ann Word, Makoto Kuro-o, Charles YC Pak, Joseph E Zerwekh

Journal:

Journal of Bone and Mineral Research

Year:

2007

Language:

english

File:

PDF, 4.58 MB

english, 2007

45

Expression of Na+/Ca2+ exchanger (NCX1) gene in the developmental mouse embryo and adult mouse brain

Koji Wakimoto, Makoto Kuro-o, Noriyuki Yanaka, Issei Komuro, Yo-ichi Nabeshima, Yuji Imai

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

2001

Language:

english

File:

PDF, 1.20 MB

english, 2001

46

Genetic Deficiency of Anti-Aging Gene Klotho Exacerbates Early Nephropathy in STZ-Induced Diabetes in Male Mice

Lin, Yi, Kuro-o, Makoto, Sun, Zhongjie

Journal:

Year:

2013

Language:

english

File:

PDF, 650 KB

english, 2013

47

Partial Reversal of Tissue Calcification and Extension of Life Span following Ammonium Nitrate Treatment of Klotho-Deficient Mice

Leibrock, Christina B., Feger, Martina, Voelkl, Jakob, Kohlhofer, Ursula, Quintanilla-Martinez, Leticia, Kuro-o, Makoto, Lang, Florian

Journal:

Kidney & Blood Pressure Research

Year:

2016

Language:

english

File:

PDF, 1.96 MB

english, 2016

48

Klotho

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2010

Language:

english

File:

PDF, 290 KB

english, 2010

49

[Advances in Experimental Medicine and Biology] Endocrine FGFs and Klothos Volume 728 || FGF21 as a Therapeutic Reagent

Year:

2012

Language:

english

File:

PDF, 156 KB

english, 2012

50

[Advances in Experimental Medicine and Biology] Endocrine FGFs and Klothos Volume 728 || FGF23 and Syndromes of Abnormal Renal Phosphate Handling

Year:

2012

Language:

english

File:

PDF, 401 KB

english, 2012

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